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Female rats can pass easily through the holes in the divider separating the two chambers, giving them the opportunity to escape the male rat. Lordosis was not reliably shown by the females, and males could intromit without the female displaying lordosis. Sex of pups was assessed by measuring anogenital distance 14 at day two after birth and confirmed at weaning. The overall implication is that male mice exhibit potent immune responses triggered by early increases in pneumococcal bacterial numberswhich are more vigorous than those in female mice, and that this increased level of response plays a key role in the progression of severe inflammation in lungs and reduced host survival. When Mogil used twelve strains of mice to measure response to morphine analgesia, he found males significantly more responsive in three strains, females in one strain, and insignificant differences between the sexes in the remaining strains.

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Food wasting by house mice:

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Why Sex Matters in Mouse Models

The females were divided into three hormone treatment groups. Female mice take longer to return to the male as coital stimulation increases; they take longer to return after an ejaculation compared to either a mount or intromission. In terms of the proportion of individuals infected and the severity of infection, human males in general have a higher burden of viral, bacterial, fungal, and parasitic diseases than females [7—10]. Sexual behavior has been carefully characterized in both male and female rats. Ten male and female mice were 8—10 weeks old when infected and weighed; the mice weighed 25—30 g Harlan.

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